Grape Seed Extract GSE has been shown for to be one of the safest active treatments against Lyme Disease - when used in a biofilm protocol.
GSE- in an animal study has been found to be a potential anti Vasculogenic (VM) mimicry agent in triple negative breast cancer cells. Vm is the unique ability of highly aggressive tumors to form new blood vessels which then are associated with invasion and metastasis.http://www.ncbi.nlm.nih.gov/pubmed/25684483
GSE may also be beneficial in the treatment of head and neck squamous cell carcinoma (HNSCC) by targeting the mitochondrial electron transport chain complex and causing oxidative and metabolic stress which leads to cytoprotective autophagy and apoptotic death in human head and neck cancer cells. Simply put, the GSE creates stress which leads to the death of the cancer cells http://www.ncbi.nlm.nih.gov/pubmed/25557495
GSE and diabetes - in this study in rats, renal injury in rats secondary to diabetes type 2 was ameliorated due to the anti inflammatory and anti oxidant effect of GSE
GSE and heart disease In a clinical trail of 287 patients with a dx of carotid plaques were divided into two groups. in the group that received 200 mg of GSE they demonstrated a significant decrease in the severity of the atheroslcerotic plaques and they also had a statistically significant decrease in cardiovascular events when compared to the control group who only received lifestyle intervention.